U.S. Organ-on-a-Chip Market by Organ Type (Liver-on-a-Chip, Heart-on-a-Chip, Lung-on-a-Chip, Kidney-on-a-Chip, Intestine-on-a-Chip, Other Organs), Application Focus (Drug Discovery and Development, Disease Modeling, Toxicology Studies, Precision Medicine, Regenerative Medicine, Others), Technology Platforms, Material Types , End-User, and Region - Partner & Customer Ecosystem (Product Services, Proposition & Key Features) Competitive Index & Regional Footprints by MarketDigits - Forecast 2023-2030

Industry : Healthcare | Pages : 178 Pages | Published On : May 2024

The U.S. Organ-on-a-Chip Market is Valued USD 38.5 Million in 2023 and projected to reach USD 214.1 Million by 2030, growing at a CAGR of 27.4% During the Forecast period of 2023-2030.

U.S. Organ-on-a-Chip Market Size

             2020                         2023-2030      

Market Size ValueUSD 38.5 Million in 2023
Market Size ValueUSD 214.1 Million by 2030
CAGR 27.4%
Forecast Period2023-2030
Base Year 2023
Historic Data2020

Major vendors in the U.S. Organ-on-a-Chip Market: AxoSim, Inc., Elveflow (Elvesys Group), Emulate, Inc., Hesperos, Inc., InSphero, Mimetas, Nortis, Inc., SynVivo, Inc., The Charles Stark Draper Laboratory, Inc., and Others.

Market Overview

The U.S. Organ-On-Chip market has experienced substantial growth in recent years, driven by factors such as increasing demand for alternatives to animal testing, advancements in microfluidic technology, and rising investments in biomedical research. One of the primary drivers of market growth is the growing focus on personalized medicine and the need for more accurate and reliable drug testing platforms. A significant trend influencing the market is the integration of advanced sensing technologies for real-time monitoring and analysis. The incorporation of sensors within OOC devices enables continuous data acquisition, offering insights into cellular behavior, biochemical changes, and other relevant parameters. Real-time monitoring enhances the capability to observe dynamic responses and assess the effects of drugs or treatments on different organs. This trend not only provides researchers with valuable information for refining OOC models but also aligns with the growing demand for precision and accuracy in experimental outcomes. As technology continues to evolve, the integration of advanced sensing capabilities is expected to be a key driver in advancing the functionality and applicability of OOC systems in various biomedical applications. Several key players in the OOC market are actively engaged in research and development activities to enhance their product offerings and gain a competitive edge. For instance, companies like Emulate Inc., TissUse GmbH, and CN Bio Innovations Limited are investing in the development of advanced OOC platforms for applications in drug discovery, disease modeling, and personalized medicine. Additionally, strategic collaborations and partnerships between academic institutions, pharmaceutical companies, and technology developers are driving innovation and accelerating market growth.

The ethical implications and limitations of animal testing

The ethical considerations and limitations associated with animal testing serve as significant catalysts for the expansion of the Organ-on-Chip (OoC) market in the United States. Ethical concerns arise from subjecting animals to potentially harmful procedures, prompting a reevaluation of testing methods. Moreover, the translatability of results from animal models to humans is hindered by physiological and genetic differences, leading to unreliable predictions of drug efficacy and safety.

OoC technology emerges as an ethical alternative by faithfully replicating human physiology on microfluidic chips, thereby diminishing reliance on animal models. This addresses societal concerns about animal welfare while furnishing more pertinent and precise data for drug development. With regulatory bodies increasingly favoring alternatives to animal testing, the demand for OoC platforms is projected to soar in the U.S. market. Consequently, the ethical imperative to minimize animal experimentation emerges as a pivotal force propelling the growth of the U.S. Organ-on-Chip market.

Market Dynamics


  • The ethical implications and limitations of animal testing
  • Demand for more predictive preclinical models
  • Rising need for rapid and cost-effective drug development
  • The increasing prevalence of chronic diseases


  • Increasing need for more efficient and cost-effective drug development processes
  • Growing trend towards personalized medicine
  • Collaborations between academic institutions and pharmaceutical companies

Increasing need for more efficient and cost-effective drug development processes

The U.S. Organ-on-a-Chip (OoC) market is poised to capitalize on the growing demand for more efficient and cost-effective drug development processes. Conventional drug development methods, known for their time-consuming and costly nature, impose significant financial strains on pharmaceutical firms. Moreover, the substantial failure rates observed in late-stage clinical trials further compound expenses and hinder timely market entry for new medications. In this landscape, OoC technology emerges as a solution, offering a streamlined and predictive approach to drug development. By faithfully reproducing human physiology on microfluidic chips, OoC platforms empower researchers to conduct rapid, high-throughput screening of drug candidates. This facilitates the swift identification of promising compounds, thus expediting the drug discovery timeline and reducing overall development expenses. With U.S. pharmaceutical companies actively seeking innovative strategies to bolster efficiency and trim costs in drug development, the demand for OoC platforms is anticipated to surge. This presents a significant opportunity for the U.S. OoC market to meet the burgeoning requirements of the pharmaceutical sector and drive advancements in drug discovery and development processes.

The liver-on-chip segments are anticipated to hold the largest market share during the forecast period

In the U.S.-U.S. Organ-on-a-Chip Market, the Organ Type segment comprises various categories such as Liver-on-a-Chip, Heart-on-a-Chip, Lung-on-a-Chip, Kidney-on-a-Chip, Intestine-on-a-Chip, and Other Organs. The dominance of liver-on-a-chip technology in the United States can be attributed to several key factors. The prevalence of liver diseases like hepatitis, cirrhosis, and liver cancer within the country has sparked substantial interest and investment in innovative technologies aimed at advancing the understanding and treatment of these conditions. The liver's pivotal role in drug metabolism and toxicity renders liver-on-a-chip platforms highly relevant for pharmaceutical research and development, which resonates with the robust presence of the pharmaceutical industry in the U.S. Furthermore, the emphasis on personalized medicine within the U.S. healthcare system accentuates the significance of liver-on-a-chip technologies, as they offer the potential to tailor drug treatments to individual patients based on their unique liver physiology.

Segmentations Analysis of U.S. Organ-on-a-Chip Market: -

  • By Organ Type
    • Liver-on-a-Chip
    • Heart-on-a-Chip
    • Lung-on-a-Chip
    • Kidney-on-a-Chip
    • Intestine-on-a-Chip
    • Other Organs
  • By Application Focus
    • Drug Discovery and Development
    • Disease Modeling
    • Toxicology Studies
    • Precision Medicine
    • Regenerative Medicine
    • Others
  • By   Technology Platforms
    • 3D Bioprinting
    • Hydrogel-Based OOC
    • Scaffold-Based OOC
  • By   Technology Platforms
    • Pharmaceutical and Biotechnology Companies
    • Academic and Research Institutions
    • Contract Research Organizations (CROs)

Recent Developments

In March 2022, Draper, a prominent supplier of organ-on-a-chip and bioprocessing systems, revealed a roadmap for its organ-on-a-chip technology, responding to the increasing emphasis on precise and innovative therapeutics in drug development.

U.S. Organ-on-a-Chip Market Report Gives Answers to Following Key Questions:

  • What will be the U.S. Organ-on-a-Chip Market’s Trends & growth rate? What analysis has been done of the prices, sales, and volume of the top producers of the U.S. Organ-on-a-Chip Market?
  • What are the main forces behind the worldwide U.S. Organ-on-a-Chip Market? Which companies dominate the U.S. Organ-on-a-Chip Market?
  • Which companies dominate the U.S. Organ-on-a-Chip Market? Which business possibilities, dangers, and tactics did they embrace in the market?
  • What are the U.S. Organ-on-a-Chip industry's suppliers' opportunities and dangers in U.S. Organ-on-a-Chip Market?
  • What is the Organ-on-a-Chip industry's regional sales, income, and pricing analysis? In the U.S. Organ-on-a-Chip Market, who are the distributors, traders, and resellers?
  • What are the main geographic areas for various trades that are anticipated to have astounding expansion over the U.S. Organ-on-a-Chip Market?
  • What are the main geographical areas for various industries that are anticipated to observe an astounding expansion in U.S. Organ-on-a-Chip Market?
  • What are the dominant revenue-generating regions for U.S. Organ-on-a-Chip Market, as well as regional growth trends?
  • By the end of the forecast period, what will the market size and growth rate be?
  • What are the main U.S. Organ-on-a-Chip Market trends that are influencing the market's expansion?
  • Which key product categories dominate the U.S. Organ-on-a-Chip Market? What are the U.S. Organ-on-a-Chip Market’s main applications?
  • In the coming years, which U.S. Organ-on-a-Chip Market technology will dominate the market?

Reason to purchase this U.S. Organ-on-a-Chip Market Report:

  • Determine prospective investment areas based on a detailed trend analysis of the U.S. Organ-on-a-Chip Market over the next years.
  • Gain an in-depth understanding of the underlying factors driving demand for different U.S. Organ-on-a-Chip Market segments in the top spending countries across the world and identify the opportunities each offers.
  • Strengthen your understanding of the market in terms of demand drivers, industry trends, and the latest technological developments, among others.
  • Identify the major channels that are driving the U.S. Organ-on-a-Chip Market, providing a clear picture of future opportunities that can be tapped, resulting in revenue expansion.
  • Channelize resources by focusing on the ongoing programs that are being undertaken by the different countries within the U.S. Organ-on-a-Chip Market.
  • Make correct business decisions based on a thorough analysis of the total competitive landscape of the sector with detailed profiles of the top U.S. Organ-on-a-Chip Market providers worldwide, including information about their products, alliances, recent contract wins, and financial analysis wherever available.



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